发明名称 FOERFARANDE FOER REDUKTION AV METIONINSULFOXIDRESTER
摘要 This application discloses a process for reducing methionine sulfoxide residues in peptides and proteins to methionine residues. The process comprises subjecting said peptide or protein to a substantially anhydrous trifluoroacetic acid reaction medium containing from about 0.01M to about 3M of an organic sulfide and from about 0.01M to about 3M of a haloacid selected from the group consisting of hydrochloric acid, hydrobromic acid, and hydroiodic acid.
申请公布号 SE8802941(L) 申请公布日期 1989.02.25
申请号 SE19880002941 申请日期 1988.08.19
申请人 LILLY CO ELI 发明人 DIMARCHI R D;LONG H B
分类号 C07K1/02;C07K1/06;C07K1/107;C07K1/113;C07K1/12;C07K7/06;C07K14/00;C07K14/575;C07K14/60;C07K14/605;C07K14/65;(IPC1-7):C07K1/06;C07K1/14 主分类号 C07K1/02
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