发明名称 |
Process for preparing rhesus antigen, medicine and pharmaceutical compositions containing the antigen and administration forms. |
摘要 |
<p>1. A process for the preparation of Rhesus antigen for oral administration, from red corpuscles of the O Rh positive group not usable in transfusion therapeutics, characterized by the following steps : a) the red corpuscles separated from plasma and the white corpuscles are washed with a solution containing a phosphate buffer, pH 7.4 and glucose ; b) after removal from the washing solution, the red corpuscles are suspended again in a solution of CaCl2 , 0.025 M, in de-ionized water ; after about 1 hour, a phospho-calcium stroma precipitate is obtained which is separated by centrifugation ; c) the phospho-calcium stroma is washed with the washing solution according to a) diluted with de-ionized water and washing is repeated several times until a whitish solution is obtained which is lyophilized.</p> |
申请公布号 |
EP0030172(A1) |
申请公布日期 |
1981.06.10 |
申请号 |
EP19800401540 |
申请日期 |
1980.10.30 |
申请人 |
OEUVRE REGIONALE DE TRANSFUSION SANGUINE DE TOULOUSE |
发明人 |
BIERME, SIMONE;BLANC, MADELEINE;ABBAL, MICHEL;FOURNIE, ALAIN |
分类号 |
A61K35/18;A61K39/00;(IPC1-7):61K39/00 |
主分类号 |
A61K35/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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