发明名称 AMINOGLYCOSIDE ANTIBIOTIC SS111A AND ITS PREPARATION
摘要 NEW MATERIAL:3-O-( beta-D-xylofuranosyl )-4-O-( 2, 6-diamino-2, 6-dideoxy-alpha-D- glucopyranosyl)-(1L)-1,3,5/2,4-5-aminocyclohaxanetetrol of the formula having the following physicochemical properties. Crystalline powder. Melting point: Indistinct and turns light yellow at 165 deg.C or above and yellow at 170 deg.C, and foams at 177 deg.C. [alpha]D+36.9+ or -0.8 deg. (c=1.021, water). Elementary analysis: C, 39.36(39.38)%; H, 7.32(7.78)%; N, 7.60(8.10)% (values in the parentheses are theoretical ones calculated as C17H33N3O11.3.5H2O). Positive to the ninhydrin and Molisch reactions; negative to the Fehling reaction, etc. USE:A medicine, a veterinary drug and disinfectant having an antimicrobial activity. PROCESS:A strain, e.g. Bacillus circulans S-11 (FERM-P No.5220), is cultivated at pH5.5-8.5 and 20-40 deg.C, preferably by the submerged culture method with aeration.
申请公布号 JPS5668699(A) 申请公布日期 1981.06.09
申请号 JP19790145129 申请日期 1979.11.08
申请人 SHIONOGI SEIYAKU KK 发明人 FUJIWARA TAMIO;TAKAHASHI TAKAO;MATSUMOTO KOUICHI;TOORI KAZUO;KONDOU EIJI
分类号 C12N1/20;A61K31/70;A61K31/7028;A61K31/7034;A61K31/7036;A61P31/04;C07H15/22;C07H15/23;C12P19/14;C12P19/46;C12R1/09 主分类号 C12N1/20
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