| 摘要 |
Title compds.(I; Ar = thienyl, phenyl, p-hydroxyphenyl, protected p-hydroxyphenyl; COB1, COB2 = carboxy or portected carboxy; Het = 1-methyl tetrazol-5-yl, 1-carboxymethyltetrazol-5-yl, 1-thia-3,4-diazol-5-yl; Y = H, MeO) were prepd. by cyclization of azetidinones(II) in inactive solvent. Thus, 650mg II (Ar = phenyl; Het = 1-methyl tetrazol-5-yl; B1, B2= phenyl; R3 = phenyl) and 5ml dioxane were refluxed for 16 hr under N2 to give 423 mg I(Ar = phenyl; Het = 1-methyltetrazol 5-yl; B1,B2 = phenyl).
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