发明名称 PROCESS FOR THE PREPARATION OF TRITERPENE DERIVATIVES
摘要 <p>The present invention provides 3.beta.-hydroxy-18.beta.-olean-9-en-30-oic acids of the formula: (I) and corresponding esters in the 3-position with mono- and dicarboxylic acids containing from 2 to 5 carbon atoms, as well as the pharmaceutically acceptable salts thereof with alkaline metals, amino acids and copper. These compounds have a pronounced anti-ulcer action and do not cause sodium retention at the effective dose levels which, together with a low toxicity of active doses, makes them very interesting pharmacologically.</p>
申请公布号 CA1102304(A) 申请公布日期 1981.06.02
申请号 CA19780298963 申请日期 1978.03.15
申请人 I/S/F SOCIETA PER AZIONI 发明人 PIFFERI, GIORGIO;UMANI-RONCHI, ACHILLE;FARINA, CARLO;GAMBA, ALFRO
分类号 A61K31/19;A61K;A61K31/20;A61K31/215;A61K31/22;A61K31/30;A61K31/56;A61P1/04;C07C;C07C51/00;C07C62/32;C07C63/42;C07C67/00;C07C69/013;C07C69/02;C07C69/145;C07C69/24;C07C69/34;C07C69/74;C07J63/00;(IPC1-7):07J63/00 主分类号 A61K31/19
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