发明名称 |
PROCESS FOR THE PREPARATION OF TRITERPENE DERIVATIVES |
摘要 |
<p>The present invention provides 3.beta.-hydroxy-18.beta.-olean-9-en-30-oic acids of the formula: (I) and corresponding esters in the 3-position with mono- and dicarboxylic acids containing from 2 to 5 carbon atoms, as well as the pharmaceutically acceptable salts thereof with alkaline metals, amino acids and copper. These compounds have a pronounced anti-ulcer action and do not cause sodium retention at the effective dose levels which, together with a low toxicity of active doses, makes them very interesting pharmacologically.</p> |
申请公布号 |
CA1102304(A) |
申请公布日期 |
1981.06.02 |
申请号 |
CA19780298963 |
申请日期 |
1978.03.15 |
申请人 |
I/S/F SOCIETA PER AZIONI |
发明人 |
PIFFERI, GIORGIO;UMANI-RONCHI, ACHILLE;FARINA, CARLO;GAMBA, ALFRO |
分类号 |
A61K31/19;A61K;A61K31/20;A61K31/215;A61K31/22;A61K31/30;A61K31/56;A61P1/04;C07C;C07C51/00;C07C62/32;C07C63/42;C07C67/00;C07C69/013;C07C69/02;C07C69/145;C07C69/24;C07C69/34;C07C69/74;C07J63/00;(IPC1-7):07J63/00 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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