PROCESS FOR PREPARING 5,6-DIARYL-1,2,4-TRIAZINE COMPOUNDS

摘要

Triazines[I; R = H or -(X)nR1 (X = O or S, n = O or 1;R1 = C1-8 alkyl, C7-8 aralkyl, C3-8 cycloalkyl or C4-8 cycloalkyl; R2,R3 = halo, C1-3 alkyl, C1-3 alkoxy or di(C1-3 alkyl)-amino; R2,R3 may not both be methoxy, if R = H or methylthio, X = Cl or mercapto; Y = halo, triphenylphosphonium halide or-o-alkali metal were manufd. by reaction of II and R1-Y. I had an antiinflammatory ED50 in erythema test 2.4μg/12cm2.