| 摘要 |
<p>For the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE : 1. A quinazoline derivative of formula I see diagramm : EP0021338,P5,F1 in D-form or as the racemate, their tautomers and salts of such compounds with mineral acids. For the Contracting State : AT 1. Process for the manufacture of a quinazoline derivative of formula I see diagramm : EP0021338,P5,F1 in D-form or as the racemate, and their tautomers as well as of salts of such compounds with mineral acids, characterized by a) brominating a compound of formula II see diagramm : EP0021338,P5,F2 in the 7-position, or b) reacting a compound of formula III see diagramm : EP0021338,P5,F3 wherein R is lower-alkyl, with cyanogen bromide, or c) treating a compound of formula IV see diagramm : EP0021338,P5,F4 wherein R has the above significance, with ammonia and isolating an obtained compound of formula I or a tautomer thereof in that form or in the form of a salt with a mineral acid.</p> |
