摘要 |
<p>A long acting liquid sulfonamide injectable composition comprising (a) water (b) from 5 to 25% w/v based on the total volume of the solution of a sulfonamide selected from sulfadimethoxine and sulfamethazine and (c) 40 to 65% w/v based on the total volume of the solution of a co-solvent selected from 2-pyrrolidone and N-methylpyrrolidone, the composition having a pH of from 5 to 9.5. The compositions may also include from 1 to 5% w/v based on the total volume of solution of polyvinylpyrrolidone having an m.w. of 5000-100,000.</p> |