| 发明名称 |
Process for the preparation of cephalosporin derivatives |
| 摘要 |
Valuable antibiotics are obtained by reacting a compound of the formula <IMAGE> in which R<1> is acyl, or a salt or a readily hydrolysable ester thereof with 5-mercapto-1-tetrazoleacetic acid. The latter can be prepared by reacting sodium azide with an isocyanate of the formula ROOCCH2NCS and hydrolysing the resulting thiol ester. |
| 申请公布号 |
CH623330(A5) |
申请公布日期 |
1981.05.29 |
| 申请号 |
CH19750011345 |
申请日期 |
1975.09.02 |
| 申请人 |
BRISTOL-MYERS CO. |
发明人 |
MURRAY ARTHUR KAPLAN;ALPHONSE PETER GRANATEK;WILLIAM JOSEPH GOTTSTEIN |
| 分类号 |
C07D501/04;A61K31/545;A61K31/546;A61P31/04;C07D257/04;C07D333/24;C07D501/06;C07D501/18;C07D501/36;C07D501/57 |
主分类号 |
C07D501/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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