发明名称 Physiological preparation containing loaded cells in suspension and a magnetic agent for local concentration thereof in a living body
摘要 Magnetic substances in particles of a diameter in the range between 1 and 20 nm are suspended in the physiological solution by which cells are loaded with materials when their cell membranes have increased permeability, the magnetic materials being provided in such dosing, that when the cells are loaded, separated from the loading solution and prepared for use in a fresh physiological solution, thereafter injected to a living body, they can be collected and held fast at a predetermined location, for example, at the location of a tumor, by the effect of an external magnetic field. Ferritin, magnetite, cobalt ferrite, nickel ferrite and other ferrimagnetic, ferromagnetic or even paramagnetic compounds can be incorporated into loaded cells for this purpose.
申请公布号 US4269826(A) 申请公布日期 1981.05.26
申请号 US19770859563 申请日期 1977.12.12
申请人 KERNFORSCHUNGSANLAGE JULICH GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 ZIMMERMANN, ULRICH;PILWAT, GUENTER
分类号 A61K9/50;A61K35/12;A61K35/18;A61K45/08;C12N13/00;(IPC1-7):A61K35/14;A61K37/48;A61K43/00 主分类号 A61K9/50
代理机构 代理人
主权项
地址