| 摘要 |
NEW MATERIAL:A substance TH69E having the following properties: Elementary analysis: C, 24.25%; H, 4.46%; N, 6.55%. Molecular weight: about 600,000+ or - 15,000 (Biogel P-series column). White amorphous powder. Decomposition point: 180 deg.C (browned by the capillary method with a silicone oil WF-30). pH of the aqueous solution 6.7-7.1. Soluble in water; insoluble in ethanol, acetone, n-hexane, etc. Positive to the phenol-sulfuric acid, anthrone and Molisch reactions, etc.; negative to the Elson-Morgan reaction, etc. USE:A carcinostatic agent, a preventive and remedy for infectious diseases, an interferon inducer and a remedy for fibrosis. PROCESS:A strain, e.g. Streptococcus faecalis And. & Hord. TH-001 (FERM-P No.4861), belonging to the genus Streptococcus, is cultivated an aerobically, perferably at 37 deg.C, for 24-48hr, and the titled substance is separated and purified. |
