| 摘要 |
<p>PURPOSE:To prepare a substituted phenoxycarboxylic acid derivative useful as a raw material for agricultural chemicals effectively, by reacting a specific substituted phenol with an alkyl halide in the presence of a base and a phase transfer catalyst. CONSTITUTION:A substituted phenol, e.g. 2,4-dichlorophenol or hydroquinone, expressed by formula I (R<1> is OH; R<2> is H, halogen, nitro, cyano, lower alkyl or trifluoromethyl) is reacted with an alkyl halide, e.g. 2-bromopropionic acid, expressed by the formual R<3>-X [R<3> is formulas II, III, IV and V (R<4> and R<5> are Hs or lower alkyls)] in the presence of a base, e.g. potassium carbonate, and a phase transfer catalyst, e.g. benzyltriethylammonium chloride, to give a substituted phenoxycarboxylic acid derivative of formula VI.</p> |
