IMMUNOLOGICAL MATERIAL BONDED TO CARBOXYLATED LATEX POLYMER AND PROCESS FOR MAKING IT

摘要

RAN 4093/34 Process for the manufacture of a water-insoluble immunological diagnostic reagent having a specific gravity of about that of water comprising discrete particles of an immunologically inert carboxylated latex polymer having condensed thereto through an amide linkage a known immunologically active material, characterized in that in a first step the immunologically inert carboxylated latex polymer substantially free from any contaminating amino compound is mixed with a water-soluble activating agent and in a second step the known immunologically active material is added;and the reagent obtained by said process.