摘要 |
NEW MATERIAL:A polysaccharide, KS-2-D, having the following physical and chemical properties. Elemental analysis, C 42.3+ or -1.5%, H 6.2+ or -0.3%, N 0.6+ or - 0.2%, ash 6.7+ or - 2.5%; molecular weight, 30,000-70,000, average molecular weight, 70,000; white amorphous powder; decomposition point, 185 deg.C (Capillary method); pH=7-8, nearly neutral; soluble in water, insoluble in ethanol, acetone, n-hexane, etc.; specific rotation, [alpha]D<21>=+66.1-+97.5 deg. (average 82.9 deg.) (water, c=0.5%); positive to phenol-sulfuric acid reaction, anthron reaction, etc., negative to toluidine blue O staining; saccharide content, 65-80% (average 71%), protein content, 3.5-6% (average 4.8%), protein/saccharide ratio, 0.05-0.08 (average 0.07), etc. USE:Carcinostatic agent. Preventive and remedy for diseases caused by candida, Pseudomonas aeruginosa, Listeria, influenza virus, etc. PROCESS:The compound can be prepared by culturing strain of Lentinus edodes KSLE 28 (FERM-P No.4196), etc. |