| 摘要 |
Title compds.(I; n = 2,3; N=B is diethylamino, amino, methylamino, dimethylamino) and their acid salts, useful as antidepressants or anodynes, were prepd. by reduction of compound contg. 1-(3-aminopropyl)-3,4-diphenyl-1H-pyrazole and 2 mole formaldehyde in the presence of catalyst. Thus, 11.5 g 1-(3-aminopropyl)-3,4-diphenyl-1H-pyrazole and 60 ml aq. form-aldehyde(35 %) were reduced at 5 psi in 125 ml ethanol in the presence of platinum oxide to give 6.6 g 1-[3-(N,N-dimethylamino)propyl -3,4-diphenyl-1H-pyrazole dihydrochloride.
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