Acetazolamide or methazolamide anti:glaucoma compsn. - is buffered at pH 6-9, using an aminoacid, esp. l-lysine, for local administration e.g. as an eyewash

摘要

Antiglaucoma medicament, for local admin. contains acetazolamide, (I), or methazolamide, (II), in aq. soln. at pH 6-9.5, pref. 7-9. Used for treatment of ocular troubles esp. glaucoma. Compsn. is suitable for local application, pref. in the form of an eyewash. The pref. medicament is (I) in soln. in an amino acid buffer, esp. L-lysine buffer. Solns. pref. contain 0.2-10 wt.%, esp. 1-5 wt.% of (I).