| 摘要 |
This invention relates to a treatment for skin disorders characterized by cracking, flaking or scaling of hands, feet or the body commonly known as "dry skin", and specifically to compounds which have been found to be effective when topically applied to prevent as well as heal the skin lesions associated with these conditions in humans. The symptoms of dry skin in humans may be alleviated by the topical administration of a therapeutically effective amount of a composition comprising the reaction product of A) at least one reactant selected from the group consisting of citric acid, glycolic acid, glucuronic acid, galacturonic acid, glucuronolactone, gluconolactone, ?-hydroxybutyric acid, ?-hydroxyisobutyric acid, lactic acid, malic acid, mandelic acid, mucic acid, pyruvic acid, methyl pyruvate, ethyl pyruvate, .beta.-phenyllactic acid, .beta.-phenylpyruvic acid, saccharic acid, tartaric acid, tartronic acid, and .beta.-hydroxybutyric acid, andB) a base selected from the group consisting of ammonium hydroxide, an organic primary, secondary, or tertiary alkylamine, alkanol amine, diamine, dialkylamine, dialknnolamine, alkylalkanol amine, trialkylamine, trialkanol amine, dialkyl alkanol amine, or alkyl dialkanolamine wherein the alkyl or alkanol substituent has from 1 to 8 carbon atoms; in a pharmaceutically acceptable vehicle. |
