| 摘要 |
Aryl substituted furnaces and pharmaceutically acceptable acid addition salts thereof according to the following formula <IMAGE> (I) wherein R1 and R2 may be the same or different and are selected from hydrogen, halogen, alkyl and acylamino having 1 to 4 carbon atoms, R3 and R4 may be the same or different and are selected from hydrogen and methyl, R5 is selected from hydrogen, dimethoxyphenyl and acylamino having the following formula R6-CONH- wherein R6 is selected from alkyl having 1 to 4 carbon atoms, are disclosed which are useful as anti-hypertensive and beta -adrenolytic agents. Also, substituted furnaces having the formula <IMAGE> (III) wherein R7 is selected from hydrogen, benzyl, the radical <IMAGE> and the radical <IMAGE> wherein X is selected from chlorine and bromine, are disclosed which are useful in the preparation of the aryl substituted furnaces. Compositions containing the aryl substituted furnaces, and methods of preparation are also disclosed.
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