Fungicidal N-polyoxyethylene:oxy-acetyl-N-phenyl-alanine derivs. - prepd. by N-acylation of N-phenyl-alanine deriv. with oxyethylated acetic acid deriv.

摘要

New polyoxyethyleneoxy-substd. acetanilide derivs. are cpds. of formula (I): R1 is 1-4C alkyl, 1-4C alkoxy, or halogen; R2 is H, 1-3C alkyl, 1-4C alkoxy, or halogen, R3 is H, 1-3C alkyl, 1-4C alkoxy, or halogen; R4 is -CO-O-R6 or -CO-S-R6; R5 is 1-6C alkyl or 1-4C alkenyl; R6 is Me or Et; and n is 1, 2, 3, 4 or 5. (I) have fungitoxic activity against phytopathogenic fungi, esp. those of the class Phycomycetes. In some cases, their action is curative, and many of the cpds. (I) are active systemically. Results of tests demonstrating the fungicidal activity of (I) are given in the specification; thus, spraying tomato plants with a 0.06% dispersion of (I; R1 and R5 are Me, R2 and R3 are H, R4 is COOMe; n is 1) affords complete protection against subsequent infection with a spore suspension of Phytophthora infestans.