发明名称 Flavin adenine dinucleotide-labeled protein and polypeptide conjugates.
摘要 <p>Flavin adenine dinucleotide-labeled conjugates of the formula: <Chemistry id="chema01" num="0001"><Image id="ia01" he="50" wi="124" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein Riboflavin (Phos) <Sub>2 </Sub>Ribose represents the riboflavin- pyrophosphate-ribose residue in flavin adenine dinucleotide (FAD), (NH) L is a protein or polypeptide (e.g., an immunoglobulin) bound through an amino group thereof, n is an integer from 2 through 10, m is an integer from 1 through 10, and p is on the average from 1 to the number of available amino groups in L. The FAD-labeled conjugates are useful as reagents in specific binding assays (e.g., immuoassays) to determine the conjugated protein or polypeptide, or a specific binding analog or partner thereof, in the liquid media.</p>
申请公布号 EP0027631(A1) 申请公布日期 1981.04.29
申请号 EP19800106251 申请日期 1980.10.15
申请人 MILES LABORATORIES INC. 发明人 CARRICO, ROBERT JOSEPH;NGO, THAT TJIEN
分类号 G01N33/532;A61K39/00;C07H19/20;C07H19/207;C07H21/00;C07K14/00;C12N9/04;G01N33/533;G01N33/535;(IPC1-7):07G7/00 主分类号 G01N33/532
代理机构 代理人
主权项
地址