发明名称 REMEDY FOR MALIGNANT TUMOR
摘要 PURPOSE:A remedy for a malignant tumor having extremely improved inhibition against tumor multiplication, reducing side effects, obtained by blending cyclophosphamide as a carcinostatic with tramexamic acid. CONSTITUTION:Cyclophosphamide(chemical name: 2-[bis(2-chloroethyl)-amino] tetrahydro-2H-1,3,2-oxazaphosphorin-2-oxide hydrate) is used together with tramexamic acid, antiplasmin. In administration tranexamic acid is preferably applied after medication of cyclophosphamide. A dose of cyclophosphamide is 20-50mg/kg, and a dose of tranexamic acid is about 1.0-3.0g/kg. The presence of tranexmic acid specifically reduces the amount of cyclophosphamide to be used and lowers side effects extremely.
申请公布号 JPS5646816(A) 申请公布日期 1981.04.28
申请号 JP19790123348 申请日期 1979.09.26
申请人 DAIICHI SEIYAKU CO 发明人 OGAWA HIDEMASA;TANAKA NORIKO
分类号 A61K31/195;A61K31/675;A61P35/00 主分类号 A61K31/195
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