| 摘要 |
Substituted benzamides (I; A = H, C1-5 alkyl or alkenyl; X = H, C1-5 alkoxy, C1-5 alkyl, C2-5 alkenyloxy, or C2-5 alkenyl; Y = H, halogen, nitro, C1-5 alkoxy ; Z = H, halogen, C1-5 alkoxy, C1-5 alkyl sulfonyl, SO2NR1R2; W = alkylene, P = hydroxy; B = NR1R2, R1 = C1-5 alkyl, R = C1-5 alkanol) were manufd. by reaction of II with NH2WB. I is proved to be antiemetics of low toxicity which is more effective than chloropromazine.
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