摘要 |
NEW MATERIAL:Antibiotic FA-1180A. Properties: amphoteric dark red powder; melting point: 186-188 deg.C; elemental analysis values: C 60.9%, H 6.2%, N 2.4%. Antibiotic FA-1180 B. Properties: amphoteric dark red powder; melting point: 198-215 deg.C; elemental analysis values: C 59.9%, H 5.4%, N 2.3%. Antibiotic FA-1180 C(as a hydrochloric acid salt). Properties: amphoteric red powder; melting point: 184-187 deg.C; elemental analysis values: C 57.1%, H 5.1%, N 2.6%, and their salts. USE:An antibacterial agent and carcinostatic. Extremely effective against various kinds of Gram-positive bacteria. PROCESS:A strain of actinomycete FA-1180 (FERM-P 5155) is subjected to liquid cultivation, and the desired substance is extracted form the filtrate or mold using a solvent or an adsorbent, and purified to give antibiotics FA-1180 A, B, or C. |