| 摘要 |
Oxayohimbane derivatives of the formula <IMAGE> in which R1 is a hydrogen, alkoxycarbonyl, alkoxycarbonylalkyl or alkylcarbonyl or a phenoxycarbonyl radical in which the phenyl radical thereof is unsubstituted or is substituted by a halogen atom or a nitro radical and R2 is a hydroxyl or OM radical, M representing an alkali metal or alkaline earth metal, or is an alkoxy, cycloalkylalkoxy, cycloalkoxy, -NH2, alkylamino, dialkylamino or cycloalkylamino radical, with the exception of the compounds in which simultaneously R1 is H and R2 is CH3O or OH, in which definitions alkoxy and alkyl have from 1 to 4 carbon atoms, and cycloalkyl has from 3 to 6 carbon atoms, and their pharmaceutically acceptable acid addition salts, which are useful in therapy for combatting behavioural disorders and epileptic vertigo, can be prepared from raubasine by known methods. |
