发明名称 Antibacterial sulphonamides, processes for their preparation and compositions containing them.
摘要 <p>Compounds of formula(II): &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="24" wi="94" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein Y is &lt;Chemistry id="chema02" num="0002"&gt;&lt;Image id="ia02" he="9" wi="54" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;and &lt;Chemistry id="chema03" num="0003"&gt;&lt;Image id="ia03" he="11" wi="26" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;Z represents a divalent radical derived from a C&lt;Sub&gt;1-20&lt;/Sub&gt; alkane, C&lt;Sub&gt;3-8&lt;/Sub&gt; cycloalkane, C&lt;Sub&gt;2-20&lt;/Sub&gt; alkene, arene, aralkane, cycloalkylalkane, heterocycle, or heterocylylalkane; and R&lt;Sup&gt;x&lt;/Sup&gt; and R&lt;Sup&gt;Y&lt;/Sup&gt; are the same or different and each represent (a) hydrogen, or (b) C&lt;Sub&gt;1-20&lt;/Sub&gt; alkyl, C&lt;Sub&gt;2-8&lt;/Sub&gt; alkenyl, either of which may be optionally substituted with C&lt;Sub&gt;3&lt;/Sub&gt;-&lt;Sub&gt;7&lt;/Sub&gt; cycloalkyl, halogen, carboxy, C&lt;Sub&gt;1-6&lt;/Sub&gt; alkoxycarbonyl, carbamyl, aryl, heterocyclyl, hydroxy, C&lt;Sub&gt;I&lt;/Sub&gt;-&lt;Sub&gt;6&lt;/Sub&gt; alkanoyloxy, amino, mono- or di-(C&lt;Sub&gt;1-6&lt;/Sub&gt;) alkylamino; or (c) C&lt;Sub&gt;3&lt;/Sub&gt;-&lt;Sub&gt;7&lt;/Sub&gt; cycloalkyl optionally substituted with C&lt;Sub&gt;1-6&lt;/Sub&gt; alkyl; or (d) aryl; or (e) heterocyclyl; or (f) R&lt;Sup&gt;x&lt;/Sup&gt; and R&lt;Sup&gt;Y&lt;/Sup&gt; together with the nitrogen atom to which they are attached represent a C&lt;Sub&gt;5-7&lt;/Sub&gt; heterocyclic ring, are useful as antibacterial and antimycoplasma agents.</p>
申请公布号 EP0026611(A1) 申请公布日期 1981.04.08
申请号 EP19800303250 申请日期 1980.09.16
申请人 BEECHAM GROUP PLC 发明人 ROGERS, NORMAN HAROLD;O'HANLON, PETER JOHN
分类号 A61K31/35;A61K31/351;A61P31/04;C07D309/10;(IPC1-7):61K31/335;07D407/06;07D309/10 主分类号 A61K31/35
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