发明名称 PROMOTION OF THROMBOLYTIC ACTIVITY OF UROKINASE WITH CRUDE DRUG EXTRACT* AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME
摘要 PURPOSE:To promote the thrombolytic activity of urokinase, by combining a urokinase-containing thrombolytic agent with a crude drug. CONSTITUTION:A urokinase-containing thrombolytic agent is administered together with the extract of one or more crude drugs selected from ''ninjin'' (root of Panax ginseng C.A. MEYER), ''suiten'', ''bochu'', ''tonin'' (stone of Prunus armeniaca LINNAEUS) and ''kyonin'' (stone of Prunus sibiricus LINNAEUS) to promote the thrombolytic activity of urokinase. The amount of the crude drug extract is 0.002- 2 grams per 1,000 unit of urokinase. The purification of urokinase is difficult, and the purified urokinase is expensive and sometimes causes safety troubles; however, the combined use of safe crude drug increases the thrombolytic activity to twofold to ten-odd times.
申请公布号 JPS5632423(A) 申请公布日期 1981.04.01
申请号 JP19790109838 申请日期 1979.08.28
申请人 SUNSTAR HAMIGAKI 发明人 IIDA SEIICHI;KUBO MICHITOKU
分类号 A61K35/62;A61K35/64;A61K36/00;A61K36/25;A61K36/73;A61K38/46;A61P7/02 主分类号 A61K35/62
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