4'-0-METHYL DERIVATIVES OF DAUNOMYCIN,ADRIAMYCIN AND OF THEIR 4'-EPI FORMS AND PROCESS FOR THEIR PREPARATION

摘要

Disclosed is a new class of antitumor glycoside antibiotics of the formula (IA): <IMAGE> (IA) wherein R is hydrogen or hydroxy; and X is <IMAGE> These compounds are prepared, using novel intermediates, by condensing the appropriate aglycone and amino-deoxy sugar to form the alpha -glycosidic linkage.