| 摘要 |
<p>1H-pyrazoles, said compounds having the formula: , said compounds being useful as anti-depressants and analgesics, are prepared by reduction with an alkali metal aluminum hydride of an .omega.-¢1-(3,4-diphenyl-1H-pyrazolyl)!-lower alkanamide; reduction with hydrogen in the presence of ammonia, methylamine, dimethylamine or diethylamine over a catalyst of a 1-(cyano-lower-alkyl)-3,4-diphenyl-1H-pyrazole; reaction of a 1-(tosyloxy-lower-alkyl)-3,4-diphenyl-1H-pyrazole with a lower-alkylamine; reaction of 3,4-diphenylpyrazole with a halo-lower-alkylation in the presence of an acid acceptor; or reductive alkylation with formaldehyde of a 1-(3-aminopropyl)-3,4-diphenyl-1H-pyrazole.</p> |
