发明名称 7-(2-(AMINO-4-THIAZOLYL)-2-((1-CARBOXY-1,1-DIALKYL)-ALKOXYIMINO)ACETAMIDO)CEPHEM SULFOXIDES
摘要 Compounds of the formula <IMAGE> wherein R is hydrogen, sodium, potassium, or certain ester groups; R1 is in the alpha -configuration and is hydrogen or methoxy; R2 and R3 are independently selected from methyl, ethyl, i-propyl, and n-propyl; R4 is hydrogen, sodium, potassium or certain ester groups, and X is hydrogen, <IMAGE> +TR <IMAGE> R6 is hydrogen or lower alkyl; R7 is hydrogen, lower alkyl, <IMAGE> or -(CH2)n-N-(lower alkyl)2; R8 is hydrogen, sodium or potassium; n is an integer from 1 to 4; are disclosed. These compounds are useful as antibacterial agents.
申请公布号 ZA8001787(B) 申请公布日期 1981.03.25
申请号 ZA19800001787 申请日期 1980.03.26
申请人 E R SQUIBB & SONS INC 发明人 SYKES R;CIMARUSTI C;KOSTER W
分类号 A61K31/545;A61K31/546;A61P31/04;C07D209/48;C07D277/20;C07D501/20;C07D501/36;C07D501/46;C07D501/57 主分类号 A61K31/545
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