发明名称 PROCESS FOR PREPARING 1-THIAZOLI-NYL-5(6)-SUBSTITUTED-BENZIMIDAZOLES
摘要 Anti-viral title compds.[I; R = H, C1-4 acyl; R1 = (R2) R3C(OH)-(where, R2 is C1-3 cycloalkyl, C3-6 cyclo alkyl methyl, C3-6 cycloalkyl ethyl, (R2)R4:C- (where, R4 is C1-7 alkylydene were prepd. II was reacted with C1-7 alkyl magnesium halide or C1-7 alkyllithium and hydrolysed to give Ia(R1 = (R2)R3COH-; R = H). Ia was dehydrated to give Ib(R1 = (R2)R4: C-; R = H) and acylation of Ib gave I.
申请公布号 KR810000232(B1) 申请公布日期 1981.03.23
申请号 KR19770000374 申请日期 1977.02.19
申请人 ELI LILLY AND CO 发明人 WIKEL J;PAGET C;CHAMBERLIN J
分类号 A61K31/415;C07D417/04;(IPC1-7):C07D417/04;A61K31/41 主分类号 A61K31/415
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