| 摘要 |
1,148,909. N<SP>1</SP>-acylated phenyl hydrazines and hydrazones. SUMITOMO CHEMICAL CO. Ltd. 13 April, 1966 [26 April, 1965 (3); 7 Dec., 1965; 8 Dec., 1965; 20 Jan., 1966; 31 Jan., 1966], No. 27273/67. Divided out of 1,148,908. Heading C2C. Novel hydrazines and hydrazones of formulµ wherein R<SP>1</SP> is an aromatic ring optionally substituted by C 1-2 alkyl, C 1-2 alkoxy or C 1-2 alkylthio or is a N, O or S containing 5- or 6-membered heterocyclic ring optionally substituted by halogen, methyl or ethyl, R<SP>6</SP> is C 1-2 alkyl, C 1-2 alkoxy, C 1-2 alkylthio, NO 2 , OH or halogen in the meta or para position to the hydrazino group and R<SP>7</SP> and R<SP>8</SP> are each H, alkyl optionally substituted by halogen, OH, alkoxycarbonyl, alkoxy or phenyl, are prepared, in the case of the hydrazones, by reaction of R<SP>1</SP>COY, where Y is a halogen or ester residue, with a compound of formula and, in the case of the hydrazines, by the same reaction with spontaneous or induced decomposition of the N-acyl hydrazones of the above formula. Pharmaceutical compositions having psychic stimulant, anti-tumour, bactericidal and fungicidal activity comprise an above novel compound and a carrier or diluent therefor. |
