| 摘要 |
Title compds. (I; R1 = phenyl, 2-thienyl, phenxoxy, R2 = H, lower alkyl, phenyl etc.; R3 = H, lower alkyl, substd. low alkyl; A = single bond, alkylene, alkenylene) and their salts are prepd. by reacting 7-acylamidocephalosporanic(II) or its carbonate with thiol compds.(III) or its carbonate. The final products(I) are broad spectrum antibiotics with low toxicity and exhibit more powerful antibacterial activity against gram negative bacteria such as Proteus vulgaris, Salmonella typhi than Cephalothin or Cefazoline.
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