发明名称 Acetoxymethyl penam compounds as beta -lactamase inhibitors
摘要 2 beta -Acetoxymethyl-2 alpha -methyl-(5R)penam-3 alpha -carboxylic acid 1,1-dioxide, pharmaceutically-acceptable salts thereof and esters thereof readily hydrolyzable in vivo; pharmaceutical compositions containing 2 beta -acetoxymethyl-2 alpha -methyl-(5R)penam-3 alpha -carboxylic acid 1,1-dioxide or salt or ester thereof; and method of enhancing the effectiveness of a beta -lactam antibiotic using 2 beta -acetoxymethyl-2 alpha -methyl-(5R)penam-3 alpha -carboxylic acid 1,1-dioxide or salt or ester thereof.
申请公布号 US4256733(A) 申请公布日期 1981.03.17
申请号 US19790079127 申请日期 1979.09.26
申请人 PFIZER INC. 发明人 BARTH, WAYNE E.
分类号 C07D499/87;A61K31/43;A61P31/04;A61P43/00;C07D;C07D471/04;C07D499/00;C07D499/04;C07D499/32;C07D499/86;C07D499/897;(IPC1-7):C07D499/00 主分类号 C07D499/87
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