发明名称 |
SETT ATT FRAMSTELLA ETT HOGRENT ENSYM MED NEDBRYTANDE VERKAN PA KARIESFRAMKALLANDE MIKROORGANISMER |
摘要 |
Method for purifying a micoorganism cells lytic enzyme by lowering the pH value of the aqueous solution containing the micoorganism cells lytic enzyme and proteases within a range of about 3.0 to 1.0 with an acid and, if necessary, by neutralizing the acidic mixture within a range of pH about 4.0 to 8.0 with an alkali and then filtering off the resulting precipitates and thereby removing off the proteases contaminated in the micoorganism cells lytic enzyme; the microorganism cells lytic enzyme being produced by cultivating a microorganism of the genus Streptomyces, e.g. S-1 strain (Streptomyces diastatochromogenes; ATCC No. 21481), H-191 strain (Streptomyces farinosus; ATCC No. 21482), H-402 strain (Streptomyces griseus var. H-402; ATCC No. 21483) and B-1829 strain (Streptomyces globisporus; ATCC No. 21553). |
申请公布号 |
SE417331(B) |
申请公布日期 |
1981.03.09 |
申请号 |
SE19730000110 |
申请日期 |
1973.01.04 |
申请人 |
* DAINIPPON PHARMACEUTICAL CO LTD |
发明人 |
Y * YOSHIMURA;K * YOKOGAWA;S * NISHIMURA |
分类号 |
C12N9/52;A61K8/66;A61K38/46;A61Q11/00;C12N9/14;C12N9/99;(IPC1-7):12N9/14 |
主分类号 |
C12N9/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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