发明名称 DCC388V AND ITS PREPARATION
摘要 NEW MATERIAL:DC-38-V, and antitumorigenic agent, having the structural formula of the formula. Melting point: 254+ or -2 deg.C (decomp.); elemental analysis: H: 5.23%, C; 65.69%; infrared absorption spectrum (KBr): Figure (1); Molecular weight: 494 (determined through mas spectroscopy); molecular formula: C27H26O9; specific rotatory power: [alpha]D<20>=-246 deg.+ or -10 deg. (C=0.5 in dimethyl sulfoxide); Solubility: easily soluble in dimethyl sulfoxide, dimethylformamide and so on, insoluble in water and petroleum ether. USE:Carcinostatic agent and remedy for infectious diseases: it has antibacterial activity against various kinds of bacteria. PREPARATION:A microorganism, which belongs to Streptomyces and can produce DC-38-V, e.g., Streptomyces golvotanareus O-7 (FERM-4649) or Streptomyces griseologilbus 4916 (FERM-4648), is cultured in a medium to accumulate DC-38-V, which is collected.
申请公布号 JPS5622782(A) 申请公布日期 1981.03.03
申请号 JP19790098656 申请日期 1979.08.03
申请人 KYOWA HAKKO KOGYO KK 发明人 TOMITA FUSAO;MATSUDA YUZURU;SHIRAHATA KIMIKATSU;TAKAHASHI KEIICHI;NAKANO HIROFUMI;SATOU TOMOYASU;OOKUBO SHIYUUJI;NAKAMURA NOBUO
分类号 C12P17/16;A61K31/35;A61P31/04;A61P35/00;C07D407/04;C12P17/18;C12R1/465 主分类号 C12P17/16
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