发明名称 OPTICALLY ACTIVE PHENETHANOLAMINES AND METHOD FOR INCREASING CARDIAC CONTRACTILITY
摘要 Compounds of the formula (I): <CHEM> wherein: R1 is hydrogen or fluorine; R2 is hydrogen or hydroxy; R3 is hydrogen, hydroxy, fluorine, aminocarbonyl, methylaminocarbonyl, methoxycarbonyl or acetoxy; C and C both are asymmetric carbon atoms having * and ** the R absolute stereochemical configuration; with the limitation that at least one of R1 and R2 is hydrogen; or pharmaceutically acceptable salts thereof are extremely potent inotropic agents.
申请公布号 ZA7903298(B) 申请公布日期 1981.02.25
申请号 ZA19790003298 申请日期 1979.07.03
申请人 ELI LILLY AND CO 发明人 MILLS J;TUTTLE R;SCHMIEGEL K
分类号 A61K31/135;A61K31/137;A61K31/165;A61K31/215;A61K31/22;A61K31/24;A61P9/00;A61P9/04;A61P9/06;C07C51/367;C07C51/487;C07C65/32;C07C67/00;C07C213/00;C07C215/00;C07C215/20;C07C215/30;C07C215/54;C07C229/38;C07C231/00;C07C237/30;C07C243/38;C07D291/04 主分类号 A61K31/135
代理机构 代理人
主权项
地址