| 摘要 |
<p>(+,-)-cis-.alpha.-3-(2,6-Dimethyl-1-piperidinyl)propyl!-.alpha.-phenyl -2-pyridinemethanol and acid-addition salts. The compounds are pharmacological agents, especially antiarrhythmic agents. The compounds can be produced by reacting pyridyllithium with cis-.gamma.-(2,6-dimethylpiperidino)butyrophenone, or by reacting cis-1-(3-lithiopropyl)-2,6-dimethylpiperidine with 2-benzoylpyridine. Pharmaceutical compositions comprising (+,-)-cis-a-3-(2,6-dimethyl-1-piperidinyl)propyl!-a-phenyl-2-pyridinem ethanol and acid-addition salts thereof and methods for treating cardiac arrhythmia using said pharmaceutical compositions are also disclosed.</p> |
