SYNTHESIS OF NITRO-2 METHYL-2 PROPANOL-1

摘要

The known compound 2-nitro-2-methyl-1-propanol is prepared by formylation, in crystalline form of high purity and in high yields, by reacting 2-nitropropane and formaldehyde in a molar ratio between 0.9:1 and 1.1:1, in a concentrated medium and in the presence of 1 to 10 milli-equivalents of an inorganic basic catalyst per mole of 2-nitropropane, with agitation, at a temperature between 40 DEG and 58 DEG C.; the pH of the reaction medium being between 7 and 11.