发明名称 PROCEDIMIENTO PARA LA PREPARACION DE ESTERES DE SALICILAMIDA
摘要 <p>Esters of salicylamide with anti-inflammatory and analgesic action are disclosed. These esters have the following general formula: <IMAGE> (I) wherein R is a radical of an acid selected among d-2-(6'-methoxy-2'-naphtyl)-propionic acid, 2[[3-(trifluoromethyl)phenyl]-amino]-3-pyridine carboxylic acid, 2- {[3-(trifluoromethyl)-phenyl]-amino}-3-pyridincarboxylic acid, 2-(4-isobutyl-phenyl)-propionic acid, 4-allyloxy-3-chloro-phenylacetic acid, 2-(3-benzoylphenyl)-propionic acid, 2-[(2,3-dimethylphenyl)amino]-benzoic acid and 2[[3-trifluoromethyl)phenyl]-amino]benzoic acid. The process for preparing the subject esters comprises reacting a halide, preferably a chloride of the desired acid, with a solution of salicylamide.</p>
申请公布号 ES489518(D0) 申请公布日期 1981.02.16
申请号 ES19180004895 申请日期 1980.03.13
申请人 NEOPHARMED S.P.A. 发明人
分类号 A61K31/60;A61K31/215;A61P25/04;A61P29/00;C07C67/00;C07C231/00;C07C231/12;C07C235/46;C07D213/80;(IPC1-7):07C103/22;61K31/615 主分类号 A61K31/60
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