摘要 |
<p>Disclosed are compounds of the formula useful in reducing the intra-ocular pressure in mammalian patients wherein R is a straight or branched chain alkanoyl group having from 2-8 carbon atoms or with Y being a straight or branched chain alkylene group having from 1-8 carbon atoms; a is an integer from 1-4; b is an integer from 1-4; X is CH2, O, S, or NR1 with R1 being hydrogen or lower alkyl with the limitation that when X is O, S, or NR1, the sum of a and b is 3 or 4, and pharmaceutically acceptable acid addition salts thereof.</p> |