发明名称 3,3-DICHLORO-2-AZETIDINONE DERIVATIVES HAVING BASIC SUBSTITUENTS
摘要 <p>Novel compounds, which have antiinflammatory activity, have the formula or a pharmaceutically acceptable salt thereof, wherein X is oxygen or sulfur; R1 is alkyl, cycloalkyl or aryl; R2 is dialkylamino, 1-pyrrolidinyl, 1-piperidinyl, 4-morpholinyl, 1-piperazinyl or 4-alkyl-1-piperazinyl; A1 is a saturated bond or an alkylene group having 1 to 4 carbon atoms; and A2 is an alkylene group having 2 to 5 carbon atoms; wherein aryl is phenyl or phenyl substituted with a halogen, alkyl, alkoxy, trifluoromethyl, or nitro group; alkyl and alkoxy are groups having 1 to 6 carbon atoms; and cycloalkyl is a group having 3 to 7 carbon atoms.</p>
申请公布号 CA1094557(A) 申请公布日期 1981.01.27
申请号 CA19780304034 申请日期 1978.05.25
申请人 SQUIBB (E. R.) & SONS, INC. 发明人 KRAPCHO, JOHN;TURK, CHESTER F.
分类号 C07D205/08;(IPC1-7):07D205/08;07D295/10 主分类号 C07D205/08
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