| 摘要 |
: This invention relates to a new process for the preparation of 2-(2-thenoylthio)-propionylglycine (I), characterized by the fact that a salt of thiophene-2-thiolcarboxylic acid (II) is reacted with (2-halopro-pionyl)-glycine (III) according to the scheme: (II) (III) (I) where Me is a metal, preferably sodium or potassium, whereas X is halogen, preferably bromine or chlorine. This compound has remakable mucolytic and liver protective activity, and the new process of preparation achieves a higher yield and higher state of purity at lower cost. |
