发明名称 HYPOTENSOR
摘要 PURPOSE:To obtain a hypotensor, by hydrolyzing a fish protein or soya protein with a specific protease and using the obtained hydrolyzate as an active compo nent. CONSTITUTION:A fish protein or soya protein is hydrolyzed with at least one kind of enzyme selected from serine protease originated from Bacillus genus bacteria, metal protease originated from Bacillus genus bacteria, thiol protease originated from vegetables and an enzyme preparation containing at least one of the above enzymes. The hydrolyzate obtained by the above process contains >=40wt% peptide having a molecular weight of 200-2,000 and is used as an active component of the objective hypotensor. The agent has excellent hypoten sive activity and extremely high safety and is producible in large quantities at a low cost. It can be administered orally, by intravenous injection or as a component of untrient drink, soya milk, etc. Dose: 0.1-500mg/kg daily.
申请公布号 JPS62169732(A) 申请公布日期 1987.07.25
申请号 JP19860011421 申请日期 1986.01.22
申请人 LION CORP 发明人 TAKADA KOJI;SUGIYAMA KEIKICHI;YAMAMOTO IKUO
分类号 A61K38/00;A61K35/60;A61K36/00;A61K36/18;A61K36/48;A61P9/12 主分类号 A61K38/00
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