发明名称 |
HERSTELLUNG VON HYDROXYESSIGSAEUREDERIVATEN |
摘要 |
The invention concerns novel hydroxyalkanoic acid derivatives of the formula: <IMAGE> I in which A is a straight or branched chain (2-6C)alkylene, R1 and R2 are independently hydrogen or (1-6C) alkyl, and R3 is hydrogen or (1-6C)alkyl, and when R3 is hydrogen, base-addition salts thereof; and processes for their manufacture. The compounds possess useful anti-arthritic properties and the invention also concerns pharmaceutical compositions of such compounds for use in the treatment of arthritic joint diseases. A representative compound of the invention is 2-{2-[4-(4-chlorophenyl)phenyl]-ethoxy}propionic acid. |
申请公布号 |
DD145747(A5) |
申请公布日期 |
1981.01.07 |
申请号 |
DD19790215387 |
申请日期 |
1979.09.06 |
申请人 |
IMPERIAL CHEMICAL INDUSTRIES LIMITED,GB |
发明人 |
EDGE,MICHAEL D.,GB |
分类号 |
C07C69/712;A61K31/19;A61K31/215;A61K31/22;A61P29/00;C07C45/46;C07C51/00;C07C51/367;C07C59/66;C07C67/00;C07C69/734;(IPC1-7):C07C59/70 |
主分类号 |
C07C69/712 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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