| 摘要 |
<p>Novel maytansinoids of the formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="44" wi="54" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein X is H or Cl, and Y is Cl, OH, SH, CN, NO<Sub>2</Sub>, -OR or -S(O)<Sub>n</Sub>R wherein R is alkyl, aryl, aralkyl or azaheterocyclic group which may be substituted, and n is 0, 1 or 2, have antimitotic, antitumor and antimicrobial activities.</p> |
