发明名称 HEART ACTIVE DERIVATIVES OF 1-AMINO-2,3-DIHYDROXY PROPANE
摘要 <p>Compounds of the general formula wherein R1 is selected from the group consisting of methyl, ethyl. propyl, methoxy, propargyloxy, cyano, allyloxy, acetyl, cyanomethyl, hydroxymethyl, CH3OCH2H2NHCOCH2O-, morpholino, pyrrolidino and pyrrolyl, R2 and R3 are the same or different and are each selected from the group consisting of hydrogen alkoxyalkoxy, alkyl, cyano, hydroxy, halogen, alkoxy, and hydroxymethyl provided that R2 and R3 are not both hydrogen, n is an integer 2, 3 or 4, and X is -O- or -S-. These compounds find pharmaceutical use in the treatment of cardiovascular disorders.</p>
申请公布号 CA1093096(A) 申请公布日期 1981.01.06
申请号 CA19770288290 申请日期 1977.10.06
申请人 AKTIEBOLAGET HAESSLE 发明人 CARLSSON, ENAR I.;SAMUELSSON, GUSTAV B.R.;LUNDGREN, BO T.
分类号 C07D295/08;A61K31/135;A61K31/138;A61K31/16;A61K31/275;A61K31/40;A61K31/535;A61K31/5375;A61P9/06;A61P9/08;A61P9/10;A61P9/12;A61P25/02;C07C67/00;C07C213/00;C07C217/32;C07C231/00;C07C231/12;C07C233/16;C07C235/20;C07C253/00;C07C255/53;C07C255/54;C07C313/00;C07C323/25;C07C323/62;C07D207/32;C07D207/325;C07D295/096;C07D295/12;(IPC1-7):07C93/14;07C121/75;07C103/78 主分类号 C07D295/08
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