| 摘要 |
<p>This invention relates to amines of the general formula R1 in 2 or 3 position is selected from the group consisting of -CH2CH=CH2, -OCH2CH=CH2, -OCH2C=CH, alkoxyalkyl, HOCH2CH2NHCOCH2O-, CH3OCH2CH2NHCOCH2O-and -CH=NOR, wherein R is selected from the group consisting of hydrogen or alkyl having 1 to 6 carbon atoms, R2 is selected from the group consisting of hydrogen, halogen, alkyl and alkoxy, R5 is selected from the group consisting of hydrogen and alkyl, R9 is selected from the group consisting of hydrogen and carbamyl, Y is a divalent member selected from the group c??? sisting of -0-, and -CH2, n is an integer from 0 to 5, inclusive, m is an integer from 0 to 2, inclusive, and Ar is a phenyl nucleus, whereby R1 is bound in 2 or 3 position to the phenyl, whereby Y is CH2, n is a 1 - 5, or a therapeutically acceptable acid addition salt thereof. These compounds are prepared according to known methods. They are useful in treating cardiovascular diseases by virtue of their ?-receptor activity.</p> |
