| 摘要 |
NEW MATERIAL:A compound of formula I (X1 is lower alkoxy; X2 is H, lower alkoxy; R is halogen, carbamoyl, or phenyl, pyridyl, pyrimidinyl, benzoyl which may be substituted by amino, etc.), or its acid addition salt. EXAMPLE:2-(3-Carbamoylphenylamino)-N-(3,4-dimethoxyphenetyl)acetamide. USE:Anti-tumor agent having central anti-tumor activity in contrast with the local activity of the conventional anti-tumor agent. PROCESS:The objective compound I is prepared by the method of the reaction formula (-COY is carboxylic acid, ester, acid anhydride, etc.; Z is halogen). |
