| 摘要 |
NEW MATERIAL:An antibiotic afragilimycin B. Appearance: light yellowish white amorphous powder; Melting point. 90-95 deg.C. Elementary analysis: C 60.21%, H 7.43%, N 3.04%. Specific rotatory power: [alpha]D<20>=+8.9 deg.C(C=0.66, chloroform). Solubility: soluble in benzene, chloroform, etc., slightly soluble in water, and insoluble in n-hexane, petroleum ether. Color reaction: positive to I2, KMnO4, sulfurnic acid, and anisaldehyde sulfuric acid. USE:Antimicrobial agent. Especially effective against anaerobic gram-positive and gram-positive bacteria. PROCESS:For example, Streptomyces neohygroscopicus sub sp. afragilimyceticus No.19255 (FEPM-P4505) is cultured aerobically in a solution. The desired substance is collected from a filtrate with an adsorbent, etc. and purified to give Afragilimycin B. |
