发明名称 |
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摘要 |
<p>A method for detecting lymphocyte clonal amplification in a mammal by cloning of lymphocytes so as to identify cell lines expressing a mutation at a structural gene locus and determining the structure of the T-cell receptor in the mutated clonal cell lines. Similar rearrangements of the regions of nucleic acid encoding T-cell receptor among multiple isolated clones from a single individual indicate an in vivo clonal lymphoxyte amplification event.</p> |
申请公布号 |
JP2752351(B2) |
申请公布日期 |
1998.05.18 |
申请号 |
JP19960345882 |
申请日期 |
1996.12.25 |
申请人 |
YUNIBAASHITEI OBU BAAMONTO ZA |
发明人 |
ARUBAATEINII RICHAADO JEI |
分类号 |
G01N33/53;C12N15/09;C12Q1/04;C12Q1/68;G01N33/50;G01N33/569;(IPC1-7):C12N15/09 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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